Name: BMS-248360
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212669487
Cas No:254737-87-6
常用名:BMS-248360
IUPAC:4'-({2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl}methyl)-N-(3,4-dimethyl-1,2-oxazol-5-yl)-2'-[(3,3-dimethyl-2-oxopyrrolidin-1-yl)methyl]-[1,1'-biphenyl]-2-sulfonamide
IUPAC:4'-({2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl}methyl)-N-(3,4-dimethyl-1,2-oxazol-5-yl)-2'-[(3,3-dimethyl-2-oxopyrrolidin-1-yl)methyl]-[1,1'-biphenyl]-2-sulfonamide
InChI key:NBDFXMDYBLSGLX-UHFFFAOYSA-N

分子式:C36H45N5O5S
分子量:659.85
氢键供体数 (HBD):1
氢键受体数 (HBA):6
LogP:5.744471
SMILES:CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C |t:4|
SMILES:CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C |t:4|

BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor. With Kis of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 shows hypertensive effects[1].

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~