Name: Glisoxepide
Rating: 5 (10 reviews)

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HIT ID:HIT212670226
Cas No:25046-79-1
常用名:Glisoxepide
别名:格列派特
IUPAC:N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide
IUPAC:N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide
InChI key:ZKUDBRCEOBOWLF-UHFFFAOYSA-N

分子式:C20H27N5O5S
分子量:449.53
氢键供体数 (HBD):3
氢键受体数 (HBA):6
LogP:1.4359764
SMILES:Cc1cc(no1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NN1CCCCCC1
SMILES:Cc1cc(no1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NN1CCCCCC1

Glisoxepide is a sulphonamide derivative and is an orally available nonselective K(ATP) channel blocker. It has antihyperglycemic activity and cardiovascular regulation effect.

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