Name: (RS)-PPG
Rating: 5 (10 reviews)

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HIT ID:HIT212670268
Cas No:120667-15-4
常用名:(RS)-PPG
IUPAC:2-amino-2-(4-phosphonophenyl)acetic acid
IUPAC:2-amino-2-(4-phosphonophenyl)acetic acid
InChI key:JRQRKFDFHAPMGQ-UHFFFAOYSA-N

分子式:C8H10NO5P
分子量:231.144
氢键供体数 (HBD):4
氢键受体数 (HBA):6
LogP:-2.5557668
SMILES:NC(C(O)=O)c1ccc(cc1)P(O)(O)=O
SMILES:NC(C(O)=O)c1ccc(cc1)P(O)(O)=O

(RS)-PPG is a potent and selective group III mGluRs agonist(EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively),with neuroprotective and anticonvulsive activity.

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