Name: BACE-1 inhibitor 1
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212670977
Cas No:1262858-14-9
常用名:BACE-1 inhibitor 1
IUPAC:N-{3-[(3R)-5-amino-3-(difluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-4-fluorophenyl}-5-bromopyridine-2-carboxamide
IUPAC:N-{3-[(3R)-5-amino-3-(difluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-4-fluorophenyl}-5-bromopyridine-2-carboxamide
InChI key:WLOOOUPMVOAGDW-KRWDZBQOSA-N

分子式:C17H14BrF3N4O2
分子量:443.224
氢键供体数 (HBD):2
氢键受体数 (HBA):5
LogP:2.2634313
SMILES:NC1=N[C@](COC1)(C(F)F)c1cc(NC(=O)c2ccc(Br)cn2)ccc1F |t:1|
SMILES:NC1=N[C@](COC1)(C(F)F)c1cc(NC(=O)c2ccc(Br)cn2)ccc1F |t:1|

BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~