Name: Tubulysin G
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212671586
Cas No:799822-08-5
常用名:Tubulysin G
IUPAC:(2S,4R)-4-({2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[(2S,3S)-3-methyl-N-{[(3-methylbut-2-enoyl)oxy]methyl}-2-{[(2R)-1-methylpiperidin-2-yl]formamido}pentanamido]pentyl]-1,3-thiazol-4-yl}formamido)-5-(4-hydroxyphenyl)-2-methylpentanoic acid
IUPAC:(2S,4R)-4-({2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[(2S,3S)-3-methyl-N-{[(3-methylbut-2-enoyl)oxy]methyl}-2-{[(2R)-1-methylpiperidin-2-yl]formamido}pentanamido]pentyl]-1,3-thiazol-4-yl}formamido)-5-(4-hydroxyphenyl)-2-methylpentanoic acid
InChI key:QRLSJCMHFBSSJW-OEJISELMSA-N

分子式:C43H63N5O10S
分子量:842.06
氢键供体数 (HBD):4
氢键受体数 (HBA):10
LogP:3.540363
SMILES:[#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-1-[#6])-[#6](=O)-[#7](-[#6]-[#8]-[#6](=O)\[#6]=[#6](/[#6])-[#6])-[#6@H](-[#6]-[#6@@H](-[#8]-[#6](-[#6])=O)-c1nc(cs1)-[#6](=O)-[#7]-[#6@H](-[#6]-[#6@H](-[#6])-[#6](-[#8])=O)-[#6]-c1ccc(-[#8])cc1)-[#6](-[#6])-[#6]
SMILES:[#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H]-1-[#6]-[#6]-[#6]-[#6]-[#7]-1-[#6])-[#6](=O)-[#7](-[#6]-[#8]-[#6](=O)\[#6]=[#6](/[#6])-[#6])-[#6@H](-[#6]-[#6@@H](-[#8]-[#6](-[#6])=O)-c1nc(cs1)-[#6](=O)-[#7]-[#6@H](-[#6]-[#6@H](-[#6])-[#6](-[#8])=O)-[#6]-c1ccc(-[#8])cc1)-[#6](-[#6])-[#6]

Tubulysin G is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin G is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~