Name: LGD-2226
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT212672047
Cas No:328947-93-9
常用名:LGD-2226
IUPAC:6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one
IUPAC:6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one
InChI key:ULBPQWIGZUGPHU-UHFFFAOYSA-N

分子式:C14H9F9N2O
分子量:392.225
氢键供体数 (HBD):1
氢键受体数 (HBA):2
LogP:4.2792006
SMILES:FC(F)(F)CN(CC(F)(F)F)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F
SMILES:FC(F)(F)CN(CC(F)(F)F)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

LGD-2226 is a selective and orally active androgen receptor modulator (EC50: 0.2 nM, Ki: 1.5 nM for the human androgen receptor). LGD-2226 can be used for muscle wasting, osteoporosis, and sexual dysfunction.

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