Name: JTT 551
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212672418
Cas No:776309-04-7
常用名:JTT 551
IUPAC:2-{[(5-tert-butyl-1,3-thiazol-2-yl)methyl]({[4-(4-{[4-(heptan-4-yl)phenoxy]methyl}phenyl)-1,3-thiazol-2-yl]methyl})amino}acetic acid
IUPAC:2-{[(5-tert-butyl-1,3-thiazol-2-yl)methyl]({[4-(4-{[4-(heptan-4-yl)phenoxy]methyl}phenyl)-1,3-thiazol-2-yl]methyl})amino}acetic acid
InChI key:FKGBFRNVTCFMGU-UHFFFAOYSA-N

分子式:C34H43N3O3S2
分子量:605.86
氢键供体数 (HBD):1
氢键受体数 (HBA):6
LogP:8.196741
SMILES:CCCC(CCC)c1ccc(OCc2ccc(cc2)-c2csc(CN(CC(O)=O)Cc3ncc(s3)C(C)(C)C)n2)cc1
SMILES:CCCC(CCC)c1ccc(OCc2ccc(cc2)-c2csc(CN(CC(O)=O)Cc3ncc(s3)C(C)(C)C)n2)cc1

JTT 551 can be used in the research of type 2 diabetes mellitus. JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~