Name: PF-05085727
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212672818
Cas No:1415637-72-7
常用名:PF-05085727
IUPAC:4-[4-(azetidin-1-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazole
IUPAC:4-[4-(azetidin-1-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazole
InChI key:SHAVEYUXRBIMLA-UHFFFAOYSA-N

分子式:C20H18F3N7
分子量:413.408
氢键供体数 (HBD):0
氢键受体数 (HBA):5
LogP:3.3608823
SMILES:Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccc(cc1)C(F)(F)F
SMILES:Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccc(cc1)C(F)(F)F

PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) .

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~