Name: PF2562
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212672845
Cas No:1609258-91-4
常用名:PF2562
IUPAC:4,6-dimethyl-5-(2-methyl-4-{1H-pyrazolo[4,3-c]pyridin-4-yloxy}phenyl)pyrimidine
IUPAC:4,6-dimethyl-5-(2-methyl-4-{1H-pyrazolo[4,3-c]pyridin-4-yloxy}phenyl)pyrimidine
InChI key:IDIUJOHYYBNCPC-UHFFFAOYSA-N

分子式:C19H17N5O
分子量:331.379
氢键供体数 (HBD):1
氢键受体数 (HBA):4
LogP:2.6732566
SMILES:Cc1cc(Oc2nccc3[nH]ncc23)ccc1-c1c(C)ncnc1C
SMILES:Cc1cc(Oc2nccc3[nH]ncc23)ccc1-c1c(C)ncnc1C

PF2562 is a dopamine D1 ligand. It is used as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor (Ki: 113 nM). PF2562 shows activity against human D1 cAMP (EC50: 568 nM in HTRF assay).

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