Name: Latanoprost lactone diol
Rating: 5 (10 reviews)

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HIT ID:HIT212673003
Cas No:145667-75-0
常用名:Latanoprost lactone diol
别名:拉坦前列腺素内酯二醇
IUPAC:(3aR,4R,5R,6aS)-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-hexahydro-2H-cyclopenta[b]furan-2-one
IUPAC:(3aR,4R,5R,6aS)-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-hexahydro-2H-cyclopenta[b]furan-2-one
InChI key:CQVHXVLSHMRWEC-UTSKFRMZSA-N

分子式:C18H24O4
分子量:304.386
氢键供体数 (HBD):2
氢键受体数 (HBA):3
LogP:1.8652847
SMILES:[H][C@]12C[C@@H](O)[C@H](CC[C@@H](O)CCc3ccccc3)[C@@]1([H])CC(=O)O2
SMILES:[H][C@]12C[C@@H](O)[C@H](CC[C@@H](O)CCc3ccccc3)[C@@]1([H])CC(=O)O2

Latanoprost lactone diol is an important intermediate compound in the synthesis of Latanoprost. Latanoprost, classified as a prostaglandin F2α analogue, functions as an agonist for the FP prostanoid receptor, resulting in a reduction in intraocular pressure (IOP).

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