Lycopodine | CAS 466-61-5 | AnyMole

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HIT212673178

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HIT212673178

HIT ID:HIT212673178
Cas No:466-61-5
常用名:Lycopodine
IUPAC:(1R,2R,10S,13S,15R)-15-methyl-6-azatetracyclo[8.6.0.0^{1,6}.0^{2,13}]hexadecan-11-one
IUPAC:(1R,2R,10S,13S,15R)-15-methyl-6-azatetracyclo[8.6.0.0^{1,6}.0^{2,13}]hexadecan-11-one
InChI key:BCZFSDNVXODRAJ-JTTNIQEDSA-N

分子式:C16H25NO
分子量:247.382
氢键供体数 (HBD):0
氢键受体数 (HBA):2
LogP:2.7295718
SMILES:[H][C@]12C[C@@H](C)C[C@]34N(CCC[C@]3([H])C(=O)C1)CCC[C@]24[H] |THB:10:11:19:2.3.5|
SMILES:[H][C@]12C[C@@H](C)C[C@]34N(CCC[C@]3([H])C(=O)C1)CCC[C@]24[H] |THB:10:11:19:2.3.5|

Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity.

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供应商
TargetMolSC
规格
货期
10-14周
纯度
-
待询
1

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