Name: Mcl1-IN-12
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212673228
Cas No:2042211-12-9
常用名:Mcl1-IN-12
IUPAC:N-(3-nitro-4-{[2-(phenylsulfanyl)ethyl]amino}benzenesulfonyl)-4-{4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzamido}benzamide
IUPAC:N-(3-nitro-4-{[2-(phenylsulfanyl)ethyl]amino}benzenesulfonyl)-4-{4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzamido}benzamide
InChI key:PVBCFXWUROOQLS-UHFFFAOYSA-N

分子式:C45H46N4O6S2
分子量:803.01
氢键供体数 (HBD):3
氢键受体数 (HBA):7
LogP:11.056667
SMILES:Cc1cc2c(cc1C(=C)c1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc3ccccc3)c(c1)[N+]([O-])=O)C(C)(C)CCC2(C)C
SMILES:Cc1cc2c(cc1C(=C)c1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc3ccccc3)c(c1)[N+]([O-])=O)C(C)(C)CCC2(C)C

Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~