Name: Taribavirin hydrochloride
Rating: 5 (10 reviews)

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HIT ID:HIT212673378
Cas No:40372-00-7
常用名:Taribavirin hydrochloride
IUPAC:1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboximidamide hydrochloride
IUPAC:1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboximidamide hydrochloride
InChI key:PIGYMBULXKLTCJ-UHSSARMYSA-N

分子式:C8H14ClN5O4
分子量:279.68
氢键供体数 (HBD):5
氢键受体数 (HBA):8
LogP:-2.5372574
SMILES:Cl.NC(=N)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
SMILES:Cl.NC(=N)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin hydrochloride is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells and the development of hemolytic anemia [2].

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