Name: Tedalinab
Rating: 5 (10 reviews)

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HIT ID:HIT212673398
Cas No:916591-01-0
常用名:Tedalinab
别名:GRC-10693
IUPAC:(1R,7S)-N-tert-butyl-3-(2,4-difluorophenyl)-3,4-diazatricyclo[5.2.1.0^{2,6}]deca-2(6),4-diene-5-carboxamide
IUPAC:(1R,7S)-N-tert-butyl-3-(2,4-difluorophenyl)-3,4-diazatricyclo[5.2.1.0^{2,6}]deca-2(6),4-diene-5-carboxamide
InChI key:NTPZXHMTJGOMCJ-WDEREUQCSA-N

分子式:C19H21F2N3O
分子量:345.394
氢键供体数 (HBD):1
氢键受体数 (HBA):2
LogP:3.8186398
SMILES:[H][C@]12CC[C@]([H])(C1)c1c2c(nn1-c1ccc(F)cc1F)C(=O)NC(C)(C)C
SMILES:[H][C@]12CC[C@]([H])(C1)c1c2c(nn1-c1ccc(F)cc1F)C(=O)NC(C)(C)C

Tedalinab is an effective and selective cannabinoid receptor 2 agonist. Tedalinab has the potential for neuropathic pain and osteoarthritis treatment. Tedalinab has >4700-fold functional selectivity for CB2 over CB1.

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