Name: CHF-5022
Rating: 5 (10 reviews)

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HIT ID:HIT212682412
Cas No:749269-77-0
常用名:CHF-5022
别名:UNII-JO8EVV007Q, CHF5022, CHEMBL196246
IUPAC:1-[2-fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]cyclopropane-1-carboxylic acid
IUPAC:1-[2-fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]cyclopropane-1-carboxylic acid
InChI key:STSYUQWYKFKDNG-UHFFFAOYSA-N

分子式:C17H12F4O2
分子量:324.275
氢键供体数 (HBD):1
氢键受体数 (HBA):2
LogP:4.9140444
SMILES:OC(=O)C1(CC1)c1ccc(c(F)c1)-c1ccc(cc1)C(F)(F)F
SMILES:OC(=O)C1(CC1)c1ccc(c(F)c1)-c1ccc(cc1)C(F)(F)F

CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).

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