Name: AGN 205728
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212686832
Cas No:859498-05-8
常用名:AGN 205728
IUPAC:4-[(1E,3E)-3-[8,8-dimethyl-5-(4-methylphenyl)-7,8-dihydronaphthalen-2-yl]-3-(hydroxyimino)prop-1-en-1-yl]benzoic acid
IUPAC:4-[(1E,3E)-3-[8,8-dimethyl-5-(4-methylphenyl)-7,8-dihydronaphthalen-2-yl]-3-(hydroxyimino)prop-1-en-1-yl]benzoic acid
InChI key:AUKGBKLQWDXBEP-FSLFYVJCSA-N

分子式:C29H27NO3
分子量:437.539
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:7.010281
SMILES:Cc1ccc(cc1)C1=CCC(C)(C)c2cc(ccc12)\C(\C=C\c1ccc(cc1)C(O)=O)=N\O |t:8|
SMILES:Cc1ccc(cc1)C1=CCC(C)(C)c2cc(ccc12)\C(\C=C\c1ccc(cc1)C(O)=O)=N\O |t:8|

AGN 205728 is a potent and selective RARγ antagonist (Ki: 3 nM; IC95: 0.6 nM) and has no inhibition on RARα and RARβ.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~