Name: WB-308
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT212689377
Cas No:1373764-87-4
常用名:WB-308
别名:WB308
IUPAC:1-{6-fluoro-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl}-2-phenylethan-1-one
IUPAC:1-{6-fluoro-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl}-2-phenylethan-1-one
InChI key:HLKIUOZYYGXOOR-UHFFFAOYSA-N

分子式:C19H17FN2O
分子量:308.356
氢键供体数 (HBD):1
氢键受体数 (HBA):1
LogP:3.1772304
SMILES:Fc1ccc2[nH]c3CN(CCc3c2c1)C(=O)Cc1ccccc1
SMILES:Fc1ccc2[nH]c3CN(CCc3c2c1)C(=O)Cc1ccccc1

WB-308 is an EGFR inhibitor that acts by decreasing NSCLC cell proliferation and colony formation and causing G2/M arrest and apoptosis.

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