Name: ND-336
Rating: 5 (10 reviews)

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HIT ID:HIT212693171
Cas No:1807453-83-3
常用名:ND-336
别名:ND-336 hydrochloride, ND336, ND 336
IUPAC:1-(4-{4-[(thiiran-2-yl)methanesulfonyl]phenoxy}phenyl)methanamine hydrochloride
IUPAC:1-(4-{4-[(thiiran-2-yl)methanesulfonyl]phenoxy}phenyl)methanamine hydrochloride
InChI key:DRGIZFGSEKSFIC-UHFFFAOYSA-N

分子式:C16H18ClNO3S2
分子量:371.89
氢键供体数 (HBD):1
氢键受体数 (HBA):3
LogP:1.87255
SMILES:Cl.NCc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1
SMILES:Cl.NCc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1

ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.

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