Name: FR 167653 free base
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212708632
Cas No:158876-65-4
常用名:FR 167653 free base
IUPAC:1-[7-(4-fluorophenyl)-8-(pyridin-4-yl)-1H,2H,3H,4H-pyrazolo[3,2-c][1,2,4]triazin-2-yl]-2-phenylethane-1,2-dione
IUPAC:1-[7-(4-fluorophenyl)-8-(pyridin-4-yl)-1H,2H,3H,4H-pyrazolo[3,2-c][1,2,4]triazin-2-yl]-2-phenylethane-1,2-dione
InChI key:LDBDQDCZGRCZED-UHFFFAOYSA-N

分子式:C24H18FN5O2
分子量:427.439
氢键供体数 (HBD):1
氢键受体数 (HBA):5
LogP:3.9603808
SMILES:Fc1ccc(cc1)-c1nn2CCN(Nc2c1-c1ccncc1)C(=O)C(=O)c1ccccc1
SMILES:Fc1ccc(cc1)-c1nn2CCN(Nc2c1-c1ccncc1)C(=O)C(=O)c1ccccc1

FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~