Name: Disopyramide phosphate
Rating: 5 (10 reviews)

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HIT ID:HIT212708749
Cas No:22059-60-5
常用名:Disopyramide phosphate
别名:SC-13957, SC13957, SC 13957
IUPAC:4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide; phosphoric acid
IUPAC:4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide; phosphoric acid
InChI key:CGDDQFMPGMYYQP-UHFFFAOYSA-N

分子式:C21H32N3O5P
分子量:437.477
氢键供体数 (HBD):1
氢键受体数 (HBA):3
LogP:3.4684365
SMILES:OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c1ccccn1)C(C)C
SMILES:OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c1ccccn1)C(C)C

Disopyramide, a sodium channel blocker in the Class of 1a anti-arrhythmic agent, is used in the treatment of Ventricular Tachycardia. Disopyramide has a negative inotropic effect on the ventricular myocardium, resulting in a significant decrease in contractility.

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