Name: Cefroxadine
Rating: 5 (10 reviews)

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HIT ID:HIT212708763
Cas No:51762-05-1
常用名:Cefroxadine
别名:CXD, CGP-9000, CGP9000, CGP 9000, Cefroxadine. Oraspor, BRN 0587499
别名:CXD, CGP-9000, CGP9000, CGP 9000, Cefroxadine. Oraspor, BRN 0587499
IUPAC:(6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
IUPAC:(6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChI key:RDMOROXKXONCAL-UEKVPHQBSA-N

分子式:C16H19N3O5S
分子量:365.4
氢键供体数 (HBD):3
氢键受体数 (HBA):6
LogP:-3.402607
SMILES:[H][C@]12SCC(OC)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CCC=CC1)C(O)=O |c:6,22,t:19|
SMILES:[H][C@]12SCC(OC)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CCC=CC1)C(O)=O |c:6,22,t:19|

Cefroxadine is an orally active cephalosporin antibiotic with a broad spectrum and a bactericidal action. It showed excellent results in the treatment of acute uncomplicated cystitis (AUC).

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