Name: Platelet Membrane Glycoprotein IIB Peptide (296-306)
Rating: 5 (10 reviews)

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HIT ID:HIT212709488
Cas No:
常用名:Platelet Membrane Glycoprotein IIB Peptide (296-306)
常用名:Platelet Membrane Glycoprotein IIB Peptide (296-306)
IUPAC:(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-hydroxybutanamido]-3-carboxypropanamido]-3-methylbutanamido]-3-carbamoylpropanamido]acetamido}-3-carboxypropanamido]acetamido}-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-4-methylpentanoic acid
IUPAC:(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-hydroxybutanamido]-3-carboxypropanamido]-3-methylbutanamido]-3-carbamoylpropanamido]acetamido}-3-carboxypropanamido]acetamido}-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-4-methylpentanoic acid
InChI key:JWMXYHIKKHVEDG-ILIXCILWSA-N

分子式:C47H75N17O20
分子量:1198.216
氢键供体数 (HBD):21
氢键受体数 (HBA):25
LogP:-15.861206
SMILES:CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)[C@H](C)O)C(C)C)C(O)=O
SMILES:CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)[C@H](C)O)C(C)C)C(O)=O

GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane domain located within 20 amino acids of the C-terminus of the light chain.

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