Name: coagulation factor II (thrombin) B chain fragment [Homo sapiens]
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212709507
Cas No:
常用名:coagulation factor II (thrombin) B chain fragment [Homo sapiens]
常用名:coagulation factor II (thrombin) B chain fragment [Homo sapiens]
IUPAC:[(2S)-2-{[(2S)-1-[(2R)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carboxybutyl]carbamoyl}-2-carboxyethyl]carbamoyl}pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]carbamoyl}-2-[(2S)-2-{[(2S)-1-[(2R)-2-[(2R,3R)-2-[(2R)-2-[(2S)-3-carboxy-2-[(2R)-2-[(2R)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanamido]propanamido]-3-phenylpropanamido]-3-hydroxypropanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanamido]ethyl]sulfanyl
IUPAC:[(2S)-2-{[(2S)-1-[(2R)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carboxybutyl]carbamoyl}-2-carboxyethyl]carbamoyl}pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]carbamoyl}-2-[(2S)-2-{[(2S)-1-[(2R)-2-[(2R,3R)-2-[(2R)-2-[(2S)-3-carboxy-2-[(2R)-2-[(2R)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanamido]propanamido]-3-phenylpropanamido]-3-hydroxypropanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanamido]ethyl]sulfanyl
InChI key:KVIJYEDJOWXHAO-VGLQLWTHSA-N

分子式:C90H136N23O24S
分子量:1956.28
氢键供体数 (HBD):24
氢键受体数 (HBA):30
LogP:-11.169927
SMILES:[H][C@](N)(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(Cc1ccccc1)C(=O)N[C@]([H])(CO)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(=O)N[C@]([H])(Cc1cnc[nH]1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@]([H])(C[S])C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@]1([H])C(=O)N[C@]([H])(CC(O)=O)C(=O)N[C@]([H])(CCCNC(N)=N)C(O)=O)[C@]([H])(C)CC |^1:109|
SMILES:[H][C@](N)(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(Cc1ccccc1)C(=O)N[C@]([H])(CO)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(=O)N[C@]([H])(Cc1cnc[nH]1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@]([H])(C[S])C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@]1([H])C(=O)N[C@]([H])(CC(O)=O)C(=O)N[C@]([H])(CCCNC(N)=N)C(O)=O)[C@]([H])(C)CC |^1:109|

Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin. Thrombin is also active in the catalysis of many other coagulation-related reactions.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~