Name: eukaryotic translation initiation factor 3
Rating: 5 (10 reviews)

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HIT ID:HIT212709514
Cas No:
常用名:eukaryotic translation initiation factor 3
常用名:eukaryotic translation initiation factor 3
IUPAC:2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-carbamoylpropanamido)-4-methylpentanamido]-4-carbamoylbutanamido}-4-methylpentanamido)-4-methylpentanamido]-4-(methylsulfanyl)butanamido}-3-carboxypropanamido)-5-carbamimidamidopentanamido]-3-methylbutanoic acid
IUPAC:2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-carbamoylpropanamido)-4-methylpentanamido]-4-carbamoylbutanamido}-4-methylpentanamido)-4-methylpentanamido]-4-(methylsulfanyl)butanamido}-3-carboxypropanamido)-5-carbamimidamidopentanamido]-3-methylbutanoic acid
InChI key:YHPKGSLWSUCJQK-UHFFFAOYSA-N

分子式:C47H84N14O14S
分子量:1101.33
氢键供体数 (HBD):16
氢键受体数 (HBA):18
LogP:-7.6182194
SMILES:CSCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(N)CC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(O)=O
SMILES:CSCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(N)CC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(O)=O

Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated in preventing the large ribosomal subunit from binding the small subunit before it is ready to commence elongation.

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