Name: ferritin heavy chain fragment [Multiple species]
Rating: 5 (10 reviews)

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HIT ID:HIT212709515
Cas No:
常用名:ferritin heavy chain fragment [Multiple species]
常用名:ferritin heavy chain fragment [Multiple species]
IUPAC:2-{2-[6-amino-2-(2-{2-[2-(2-{2-[2-amino-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido}-3-carbamoylpropanamido)-4-carboxybutanamido]-4-carbamoylbutanamido}-3-methylbutanamido)hexanamido]propanamido}-3-methylpentanoic acid
IUPAC:2-{2-[6-amino-2-(2-{2-[2-(2-{2-[2-amino-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido}-3-carbamoylpropanamido)-4-carboxybutanamido]-4-carbamoylbutanamido}-3-methylbutanamido)hexanamido]propanamido}-3-methylpentanoic acid
InChI key:OQONEVRBHIUNDW-UHFFFAOYSA-N

分子式:C49H80N12O15
分子量:1077.248
氢键供体数 (HBD):15
氢键受体数 (HBA):17
LogP:-7.663877
SMILES:CCC(C)C(NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(N)Cc1ccc(O)cc1)C(C)C)C(O)=O
SMILES:CCC(C)C(NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(N)Cc1ccc(O)cc1)C(C)C)C(O)=O

Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21 kDA respectively. The ferritin found in cancer cells was found to consist mainly of H chains. The heavy chain of Ferritin also possesses ferroxidase activity, this involves the conversion of iron from the ferrous (Fe2+) to ferric (Fe 3+) forms [1][2][3][4].

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