Name: TLQP-21
Rating: 5 (10 reviews)

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HIT ID:HIT212709541
Cas No:869988-94-3
常用名:TLQP-21
IUPAC:(2S)-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S,3S)-2-amino-1,3-dihydroxybutylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-4-(C-hydroxycarbonimidoyl)butanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxypropylidene]amino}-1,3-dihydroxypropylidene]amino}-1,3-dihydroxypropylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino}-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino}-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino}-1-hydroxypropylidene]amino}-4-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxypropylidene]amino}-5-carbamimidamidopentanoic acid
IUPAC:(2S)-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S,3S)-2-amino-1,3-dihydroxybutylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-4-(C-hydroxycarbonimidoyl)butanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxypropylidene]amino}-1,3-dihydroxypropylidene]amino}-1,3-dihydroxypropylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino}-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino}-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino}-1-hydroxypropylidene]amino}-4-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxypropylidene]amino}-5-carbamimidamidopentanoic acid
InChI key:PWWMOXVVMRPYJS-IWCKOKPFSA-N

分子式:C107H170N40O26
分子量:2432.791
氢键供体数 (HBD):38
氢键受体数 (HBA):59
LogP:-8.538339
SMILES:[H][C@](C)(O)[C@]([H])(N)C(O)=N[C@@]([H])(CC(C)C)C(O)=N[C@@]([H])(CCC(O)=N)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=N[C@@]([H])(C)C(O)=N[C@@]([H])(CO)C(O)=N[C@@]([H])(CO)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=N[C@@]([H])(Cc1cnc[nH]1)C(O)=N[C@@]([H])(Cc1ccccc1)C(O)=N[C@@]([H])(Cc1cnc[nH]1)C(O)=N[C@@]([H])(Cc1cnc[nH]1)C(O)=N[C@@]([H])(C)C(O)=N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=N[C@@]([H])(C)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=O |w:7.7,16.16,42.44,48.50,55.57,62.64,74.76,86.88,98.100,109.112,121.125,132.137,143.149,149.155,174.182,180.188|
SMILES:[H][C@](C)(O)[C@]([H])(N)C(O)=N[C@@]([H])(CC(C)C)C(O)=N[C@@]([H])(CCC(O)=N)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=N[C@@]([H])(C)C(O)=N[C@@]([H])(CO)C(O)=N[C@@]([H])(CO)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=N[C@@]([H])(Cc1cnc[nH]1)C(O)=N[C@@]([H])(Cc1ccccc1)C(O)=N[C@@]([H])(Cc1cnc[nH]1)C(O)=N[C@@]([H])(Cc1cnc[nH]1)C(O)=N[C@@]([H])(C)C(O)=N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=N[C@@]([H])(C)C(O)=N[C@@]([H])(CCCNC(N)=N)C(O)=O |w:7.7,16.16,42.44,48.50,55.57,62.64,74.76,86.88,98.100,109.112,121.125,132.137,143.149,149.155,174.182,180.188|

TLQP 21 is a VGF-derived peptide. TLQP 21 can protect cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis and increases energy expenditure and prevents early phase diet-induced diabetes.

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
35日内发货
纯度
-
¥ 9,380.00
1

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