Name: L 652343
Rating: 5 (10 reviews)

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HIT ID:HIT212710211
Cas No:102565-09-3
常用名:L 652343
别名:L-652343, L652343, L-652,343, L652,343, L 652,343
别名:L-652343, L652343, L-652,343, L652,343, L 652,343
IUPAC:3-hydroxy-N-[(1E)-2-phenyl-2-(thiophen-2-yl)ethenyl]-5-(trifluoromethyl)-1-benzothiophene-2-carboxamide
IUPAC:3-hydroxy-N-[(1E)-2-phenyl-2-(thiophen-2-yl)ethenyl]-5-(trifluoromethyl)-1-benzothiophene-2-carboxamide
InChI key:MWRHQMNEBAXDOF-FOWTUZBSSA-N

分子式:C22H14F3NO2S2
分子量:445.47
氢键供体数 (HBD):2
氢键受体数 (HBA):2
LogP:6.734203
SMILES:Oc1c(sc2ccc(cc12)C(F)(F)F)C(=O)N\C=C(\c1cccs1)c1ccccc1
SMILES:Oc1c(sc2ccc(cc12)C(F)(F)F)C(=O)N\C=C(\c1cccs1)c1ccccc1

L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.

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