Name: L 741742 (free base)
Rating: 5 (10 reviews)

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HIT ID:HIT212710288
Cas No:156337-32-5
常用名:L 741742 (free base)
别名:L-741742, L741742, L-741,742, L 741742, L 741,742
别名:L-741742, L741742, L-741,742, L 741742, L 741,742
IUPAC:4-[5-(4-chlorophenyl)-4-methyl-1,2-oxazol-3-yl]-1-(2-phenylethyl)piperidine
IUPAC:4-[5-(4-chlorophenyl)-4-methyl-1,2-oxazol-3-yl]-1-(2-phenylethyl)piperidine
InChI key:QDMAKDIDFJTXEL-UHFFFAOYSA-N

分子式:C23H25ClN2O
分子量:380.92
氢键供体数 (HBD):0
氢键受体数 (HBA):2
LogP:5.653614
SMILES:Cc1c(noc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1
SMILES:Cc1c(noc1-c1ccc(Cl)cc1)C1CCN(CCc2ccccc2)CC1

L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).

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