Name: JNJ-28610244
Rating: 5 (10 reviews)

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HIT ID:HIT212710402
Cas No:1251462-28-8
常用名:JNJ-28610244
别名:JNJ 28610244
IUPAC:(Z)-N-[(5-methyl-1H-indol-2-yl)(1-methylpiperidin-4-yl)methylidene]hydroxylamine
IUPAC:(Z)-N-[(5-methyl-1H-indol-2-yl)(1-methylpiperidin-4-yl)methylidene]hydroxylamine
InChI key:VOIJIMTXMUBFDD-VLGSPTGOSA-N

分子式:C16H21N3O
分子量:271.364
氢键供体数 (HBD):2
氢键受体数 (HBA):3
LogP:2.5591834
SMILES:CN1CCC(CC1)C(=N\O)\c1cc2cc(C)ccc2[nH]1
SMILES:CN1CCC(CC1)C(=N\O)\c1cc2cc(C)ccc2[nH]1

JNJ-28610244 is a specific agonist of the H4 receptor. It acts by blocking Mac-1-dependent activation of p38 MAPK.

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