Name: MMV024101
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212710708
Cas No:1092565-44-0
常用名:MMV024101
别名:TCMDC-134293, TCMDC134293, TCMDC 134293, MMV-024101, MMV 024101
别名:TCMDC-134293, TCMDC134293, TCMDC 134293, MMV-024101, MMV 024101
IUPAC:5-[8-(1H-pyrazol-4-yl)-1,5-naphthyridin-2-yl]pyridine-3-sulfonamide
IUPAC:5-[8-(1H-pyrazol-4-yl)-1,5-naphthyridin-2-yl]pyridine-3-sulfonamide
InChI key:GTWOKQIGBJADIZ-UHFFFAOYSA-N

分子式:C16H12N6O2S
分子量:352.37
氢键供体数 (HBD):2
氢键受体数 (HBA):6
LogP:0.67192173
SMILES:NS(=O)(=O)c1cncc(c1)-c1ccc2nccc(-c3cn[nH]c3)c2n1
SMILES:NS(=O)(=O)c1cncc(c1)-c1ccc2nccc(-c3cn[nH]c3)c2n1

MMV024101 is a PI4K inhibitor. MMV024101 exhibits submicromolar potency against P. falciparum NF54 (IC50 =543 nM), low aqueous solubility (<5 μM), and rapid clearance by mouse liver microsomes with only 2% of parent compound remaining after 30 min of incubation.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~