Name: DCCCyb
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212711008
Cas No:1236046-15-3
常用名:DCCCyb
IUPAC:2,4-dichloro-N-{[(1s,4s)-4-cyclopropylmethanesulfonyl-1-(cyclopropylmethyl)cyclohexyl]methyl}benzamide
IUPAC:2,4-dichloro-N-{[(1s,4s)-4-cyclopropylmethanesulfonyl-1-(cyclopropylmethyl)cyclohexyl]methyl}benzamide
InChI key:PSIMLOLEQCVVJV-CXGRPWHSSA-N

分子式:C22H29Cl2NO3S
分子量:458.44
氢键供体数 (HBD):1
氢键受体数 (HBA):3
LogP:4.528398
SMILES:Clc1ccc(C(=O)NC[C@]2(CC3CC3)CC[C@@H](CC2)S(=O)(=O)CC2CC2)c(Cl)c1 |wU:9.8,16.20,wD:9.9,(5.83,3.94,;5.3,2.49,;3.79,2.23,;3.26,.78,;4.25,-.4,;3.72,-1.85,;2.21,-2.11,;4.71,-3.03,;4.19,-4.47,;5.18,-5.65,;3.84,-6.42,;3.84,-7.96,;4.61,-9.3,;3.07,-9.3,;5.7,-7.1,;7.22,-7.37,;8.21,-6.19,;7.68,-4.74,;6.17,-4.47,;9.73,-6.46,;9.46,-7.97,;9.99,-4.94,;11.24,-6.72,;11.77,-8.17,;12.95,-9.16,;11.5,-9.69,;5.77,-.13,;6.76,-1.31,;6.29,1.32,)|
SMILES:Clc1ccc(C(=O)NC[C@]2(CC3CC3)CC[C@@H](CC2)S(=O)(=O)CC2CC2)c(Cl)c1 |wU:9.8,16.20,wD:9.9,(5.83,3.94,;5.3,2.49,;3.79,2.23,;3.26,.78,;4.25,-.4,;3.72,-1.85,;2.21,-2.11,;4.71,-3.03,;4.19,-4.47,;5.18,-5.65,;3.84,-6.42,;3.84,-7.96,;4.61,-9.3,;3.07,-9.3,;5.7,-7.1,;7.22,-7.37,;8.21,-6.19,;7.68,-4.74,;6.17,-4.47,;9.73,-6.46,;9.46,-7.97,;9.99,-4.94,;11.24,-6.72,;11.77,-8.17,;12.95,-9.16,;11.5,-9.69,;5.77,-.13,;6.76,-1.31,;6.29,1.32,)|

DCCCyb is an orally bioavailable and selective GlyT1 Inhibitor. DCCCyb demonstrated excellent in vivo occupancy of GlyT1 transporters in rhesus monkeys as determined by the displacement of a PET tracer ligand.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymol随时为您提供帮助。

电话：400-820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~