Name: ML350
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212711074
Cas No:1565852-90-5
常用名:ML350
别名:SR-2311, SR2311, SR 2311, ML-350, ML 350
别名:SR-2311, SR2311, SR 2311, ML-350, ML 350
IUPAC:methyl 5-bromo-2-[(3S,4S)-4-(cyclohexylamino)-3-hydroxypiperidin-1-yl]pyridine-3-carboxylate
IUPAC:methyl 5-bromo-2-[(3S,4S)-4-(cyclohexylamino)-3-hydroxypiperidin-1-yl]pyridine-3-carboxylate
InChI key:AJYHHWYDOWTOKZ-HOTGVXAUSA-N

分子式:C18H26BrN3O3
分子量:412.328
氢键供体数 (HBD):2
氢键受体数 (HBA):5
LogP:2.9830384
SMILES:COC(=O)c1cc(Br)cnc1N1CC[C@H](NC2CCCCC2)[C@@H](O)C1
SMILES:COC(=O)c1cc(Br)cnc1N1CC[C@H](NC2CCCCC2)[C@@H](O)C1

ML350 (CYM-50202) is a KOR (IC50: 12.6 nM) antagonist with good and moderate selectivity against the DOR and MOR. CYM-50202 displayed high solubility and excellent CNS penetration. CYM-50202 did not display long-lasting pharmacodynamic effects observed with prototypical KOR antagonists.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~