Name: Garenoxacin mesylate
Rating: 5 (10 reviews)

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HIT ID:HIT212711806
Cas No:223652-82-2
常用名:Garenoxacin mesylate
别名:Garenoxacin mesilate, BMS284756, BMS 284756, BM-284756
别名:Garenoxacin mesilate, BMS284756, BMS 284756, BM-284756
IUPAC:1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; methanesulfonic acid
IUPAC:1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; methanesulfonic acid
InChI key:UPHLDCUEQOTSAD-RFVHGSKJSA-N

分子式:C24H24F2N2O7S
分子量:522.52
氢键供体数 (HBD):2
氢键受体数 (HBA):6
LogP:1.5394918
SMILES:CS(O)(=O)=O.C[C@H]1NCc2cc(ccc12)-c1ccc2c(c1OC(F)F)n(cc(C(O)=O)c2=O)C1CC1
SMILES:CS(O)(=O)=O.C[C@H]1NCc2cc(ccc12)-c1ccc2c(c1OC(F)F)n(cc(C(O)=O)c2=O)C1CC1

Garenoxacin mesylate, a novel oral des-fluoro quinolone, has potent antimicrobial activity against common respiratory pathogens, including resistant strains and Gram-negative and Gram-positive bacterial infections.

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