AM-0687 | AM 0687 | CAS 1259522-94-5 | AnyMole

有库存

HIT212712018

sdf 文件

结构编辑

类似物检索

HIT212712018

HIT ID:HIT212712018
Cas No:1259522-94-5
常用名:AM-0687
别名:AM 0687
IUPAC:2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-6-fluoro-N-methyl-3-(pyridin-2-yl)quinoline-4-carboxamide
IUPAC:2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-6-fluoro-N-methyl-3-(pyridin-2-yl)quinoline-4-carboxamide
InChI key:OLJXUPJOUSFYSX-LBPRGKRZSA-N

分子式:C23H19FN8O
分子量:442.458
氢键供体数 (HBD):3
氢键受体数 (HBA):8
LogP:2.3033843
SMILES:CNC(=O)c1c(-c2ccccn2)c(nc2ccc(F)cc12)[C@H](C)Nc1ncnc(N)c1C#N
SMILES:CNC(=O)c1c(-c2ccccn2)c(nc2ccc(F)cc12)[C@H](C)Nc1ncnc(N)c1C#N

AM-0687 is a potent and selective PI3Kδ inhibitor. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. Rat KLH: IgG ED50 -= 0.026 mg/kg; IgM ED50 = 0.016 mg/kg. Rat PK Clu = 2.3 L/hr/kg.

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
6-8周
纯度
-
¥ 10,600.00
1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

TargetMol | Target Loading

正在加载 ~