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  3. HIT212712020
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HIT212712020
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HIT212712020
  • HIT ID:HIT212712020
  • Cas No:1187917-12-9
  • 常用名:AIC-292
  • IUPAC:1-[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazole-3-carbonyl]imidazolidin-4-one
    IUPAC:1-[1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazole-3-carbonyl]imidazolidin-4-one
  • InChI key:JPOJKNJIKXMZRB-UHFFFAOYSA-N
  • 分子式:C19H12Cl2F2N4O2
  • 分子量:437.23
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):3
  • LogP:3.6369195
  • SMILES:Fc1cc(Cl)cc(c1)-c1cc(nn1-c1ccc(F)c(Cl)c1)C(=O)N1CNC(=O)C1
    SMILES:Fc1cc(Cl)cc(c1)-c1cc(nn1-c1ccc(F)c(Cl)c1)C(=O)N1CNC(=O)C1
  • AIC-292 is a potent reverse transcriptase inhibitor with well tolerated in different cell lines. In addition, activity of AIC292 could be demonstrated against a broad panel of wild-type HIV-1 group. AIC292 also retained activity against viruses harboring NNRTI resistance-associated mutations (RAMs), including the most prevalent variants, K103N, G190A and Y181C.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 11,700.00
    1

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