Name: AM-8191 HCl
Rating: 5 (10 reviews)

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HIT ID:HIT212712060
Cas No:1417548-17-4
常用名:AM-8191 HCl
别名:AM-8191, AM8191, AM 8191
IUPAC:6-[({1-[(1S)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl]-2-oxabicyclo[2.2.2]octan-4-yl}amino)methyl]-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one hydrochloride
IUPAC:6-[({1-[(1S)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl]-2-oxabicyclo[2.2.2]octan-4-yl}amino)methyl]-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one hydrochloride
InChI key:WDWFTZSOSPERQG-JKLZSTNZSA-N

分子式:C26H29ClFN5O5
分子量:546
氢键供体数 (HBD):3
氢键受体数 (HBA):9
LogP:1.7910309
SMILES:Cl.COc1ccc2ncc(F)c(C[C@H](O)C34CCC(CC3)(CO4)NCc3ccc4OCC(=O)Nc4n3)c2n1
SMILES:Cl.COc1ccc2ncc(F)c(C[C@H](O)C34CCC(CC3)(CO4)NCc3ccc4OCC(=O)Nc4n3)c2n1

AM-8191, a bacterial topoisomerase inhibitors, has broad-spectrum antibacterial activity.

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