Name: AZ10397767
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212712133
Cas No:333742-63-5
常用名:AZ10397767
别名:AZ-10397767, AZ 10397767
IUPAC:5-{[(3-chloro-2-fluorophenyl)methyl]sulfanyl}-7-{[(2R)-1-hydroxypropan-2-yl]amino}-2H,3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
IUPAC:5-{[(3-chloro-2-fluorophenyl)methyl]sulfanyl}-7-{[(2R)-1-hydroxypropan-2-yl]amino}-2H,3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
InChI key:KHTUORKUWBDRBX-SSDOTTSWSA-N

分子式:C15H14ClFN4O2S2
分子量:400.87
氢键供体数 (HBD):3
氢键受体数 (HBA):6
LogP:4.1286154
SMILES:C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2F)nc2[nH]c(=O)sc12
SMILES:C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2F)nc2[nH]c(=O)sc12

AZ10397767 is a potent CXCR2 antagonist (IC50 = 1 nM). AZ10397767 significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~