Name: BIPM
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212712250
Cas No:1070424-33-7
常用名:BIPM
IUPAC:5-{[3-(2H-1,3-benzodioxole-5-carbonyl)piperidin-1-yl]methyl}isoquinoline
IUPAC:5-{[3-(2H-1,3-benzodioxole-5-carbonyl)piperidin-1-yl]methyl}isoquinoline
InChI key:FVXLGQXTXCJFGL-UHFFFAOYSA-N

分子式:C23H22N2O3
分子量:374.44
氢键供体数 (HBD):0
氢键受体数 (HBA):5
LogP:3.2929375
SMILES:O=C(C1CCCN(Cc2cccc3cnccc23)C1)c1ccc2OCOc2c1
SMILES:O=C(C1CCCN(Cc2cccc3cnccc23)C1)c1ccc2OCOc2c1

BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2). Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits phosphorylation of cofilin, a regulatory protein of actin cytoskeleton.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~