BMS-814580 | CAS 1197420-11-3 | AnyMole

有库存

HIT212712287

sdf 文件

结构编辑

类似物检索

HIT212712287

HIT ID:HIT212712287
Cas No:1197420-11-3
常用名:BMS-814580
IUPAC:6-(4-chlorophenyl)-3-{4-[(3,3-difluoro-1-hydroxycyclobutyl)methoxy]-3-methoxyphenyl}-3H,4H-thieno[3,2-d]pyrimidin-4-one
IUPAC:6-(4-chlorophenyl)-3-{4-[(3,3-difluoro-1-hydroxycyclobutyl)methoxy]-3-methoxyphenyl}-3H,4H-thieno[3,2-d]pyrimidin-4-one
InChI key:NCXJWNAKIMMZOC-UHFFFAOYSA-N

分子式:C24H19ClF2N2O4S
分子量:504.93
氢键供体数 (HBD):1
氢键受体数 (HBA):5
LogP:4.815049
SMILES:COc1cc(ccc1OCC1(O)CC(F)(F)C1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1
SMILES:COc1cc(ccc1OCC1(O)CC(F)(F)C1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

BMS-814580 is a potent and selective functional antagonist (Kb = 117 nM) of human MCHR1. BMS-814580 exhibits potent binding affinity (Ki = 17 nM) for human MCHR1. BMS-814580 also exhibits potent binding affinities for cynomolgus monkey and rat MCHR1 (Ki of 4.9 and 11.5 nM, respectively). MCHR1 antagonist demonstrates reduction in feeding and body weight in rats and mice.

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
8-10周
纯度
-
¥ 13,900.00
1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

TargetMol | Target Loading

正在加载 ~