• CAS号
  • HIT ID
  • 供应商货号
  • SMILES
  • 化合物库

购物车
0
  2. 结构式搜索
  3. HIT212712390
有库存
HIT212712390
 sdf 文件
结构编辑
类似物检索
HIT212712390
  • HIT ID:HIT212712390
  • Cas No:1210501-46-4
  • 常用名:CL385319 HCl
  • 别名:CL385319 hydrochloride, CL-385319, CL385319, CL 385319
    别名:CL385319 hydrochloride, CL-385319, CL385319, CL 385319
  • IUPAC:3-fluoro-N-[2-(piperidin-1-yl)ethyl]-5-(trifluoromethyl)benzamide hydrochloride
    IUPAC:3-fluoro-N-[2-(piperidin-1-yl)ethyl]-5-(trifluoromethyl)benzamide hydrochloride
  • InChI key:FEMIHMMAZDXYBI-UHFFFAOYSA-N
  • 分子式:C15H19ClF4N2O
  • 分子量:354.77
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):2
  • LogP:2.9371233
  • SMILES:Cl.Fc1cc(cc(c1)C(F)(F)F)C(=O)NCCN1CCCCC1
    SMILES:Cl.Fc1cc(cc(c1)C(F)(F)F)C(=O)NCCN1CCCCC1
  • CL385319 is a potent inhibitor of H5N1 avian influenza A virus infection by blocking viral entry. CL-385319 is effective in inhibiting infection of highly pathogenic H5N1 influenza A virus in Madin-Darby Canine Kidney (MDCK) cells with an IC50 of 27.03±2.54 μM. CL385319 with low cytotoxicity (CC50=1.48±0.01 mM) could also inhibit entry of pseudoviruses carrying hemagglutinins from H5N1 strains that were isolated from different places at different times, while it had no inhibitory activity on the entry of VSV-G pseudotyped particles.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。
电话：400820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
TargetMol | Target Loading
正在加载 ~
常用功能
使用指南化合物搜索在线客服返回顶层