Name: CM-10-18
Rating: 5 (10 reviews)

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HIT ID:HIT212712401
Cas No:1159614-57-9
常用名:CM-10-18
别名:CM-1018
IUPAC:(2R,3R,4R,5S)-1-(7-ethyl-7-hydroxynonyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
IUPAC:(2R,3R,4R,5S)-1-(7-ethyl-7-hydroxynonyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
InChI key:VLVMPUBHMJVGPH-QKPAOTATSA-N

分子式:C17H35NO5
分子量:333.469
氢键供体数 (HBD):5
氢键受体数 (HBA):6
LogP:0.46042764
SMILES:CCC(O)(CC)CCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
SMILES:CCC(O)(CC)CCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

CM-10-18 is a potent inhibitor of ER α-glucosidase. CM-10-18 demonstrated superior in vitro antiviral activity against representative viruses from four viral families causing hemorrhagic fever. CM-10-18 efficiently protected the lethality of dengue virus infection of mice.

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