Name: FR-186054
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212712680
Cas No:179053-90-8
常用名:FR-186054
别名:FR186054, FR 186054
IUPAC:1-benzyl-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]-1-{[3-(1H-pyrazol-3-yl)phenyl]methyl}urea
IUPAC:1-benzyl-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]-1-{[3-(1H-pyrazol-3-yl)phenyl]methyl}urea
InChI key:XCMUCRXXBCAKCO-UHFFFAOYSA-N

分子式:C26H27N5OS2
分子量:489.66
氢键供体数 (HBD):2
氢键受体数 (HBA):3
LogP:5.8755584
SMILES:CSc1cc(C)nc(SC)c1NC(=O)N(Cc1ccccc1)Cc1cccc(c1)-c1cc[nH]n1
SMILES:CSc1cc(C)nc(SC)c1NC(=O)N(Cc1ccccc1)Cc1cccc(c1)-c1cc[nH]n1

FR-186054 is a new, potent inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) and has oral activity. Compared to other ACAT inhibitors, this compound displayed excellent in vitro efficacy, irrespective of dosing method, indicating superior characteristics.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~