Name: JNJ-26070109
Rating: 5 (10 reviews)

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HIT ID:HIT212712927
Cas No:844645-08-5
常用名:JNJ-26070109
别名:JNJ26070109
IUPAC:4-bromo-N-[(1R)-1-(2,4-difluorophenyl)ethyl]-2-(quinoxaline-5-sulfonamido)benzamide
IUPAC:4-bromo-N-[(1R)-1-(2,4-difluorophenyl)ethyl]-2-(quinoxaline-5-sulfonamido)benzamide
InChI key:TZKCPFFVWLRNRZ-CYBMUJFWSA-N

分子式:C23H17BrF2N4O3S
分子量:547.37
氢键供体数 (HBD):2
氢键受体数 (HBA):5
LogP:4.056265
SMILES:C[C@@H](NC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nccnc12)c1ccc(F)cc1F
SMILES:C[C@@H](NC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nccnc12)c1ccc(F)cc1F

JNJ-26070109, an antagonist of cholecystokinin CCK2 receptor, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.

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