Name: OMDM169
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212713157
Cas No:130193-44-1
常用名:OMDM169
别名:OMDM-169, OMDM 169
IUPAC:(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl 2-formamidoacetate
IUPAC:(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl 2-formamidoacetate
InChI key:ANPULBVRORHAGO-VABKMULXSA-N

分子式:C25H45NO5
分子量:439.637
氢键供体数 (HBD):1
氢键受体数 (HBA):3
LogP:6.2837033
SMILES:CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)CNC=O
SMILES:CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)CNC=O

OMDM169 is a potent and selective MAGL inhibitor. OMDM169 could enhances 2-AG levels and of exerts analgesic activity via indirect activation of cannabinoid receptors. OMDM169 exhibited 0.13 microM<IC(50)<0.41 microM towards 2-AG hydrolysing activities in rat cerebellum and COS-7 cells, and inhibited the human recombinant MAGL (IC(50)=0.89 microM), whilst being inactive at human CB(1) and CB(2) receptors (K(i)>10 microM).

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~