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- HIT ID:HIT212713270
- Cas No:131505-02-7
- 常用名:PD 130908
- 别名:PD-130908, PD130908
- InChI key:SZKHTAVHHLGWQG-UHFFFAOYSA-N
- 分子式:C8H14Br2N4O2
- 分子量:358.034
- 氢键供体数 (HBD):1
- 氢键受体数 (HBA):4
- LogP:1.2482275
- PD 130908 is an analogue of RSU 1069 with effective hypoxic cytotoxin, but less potent than RSU 1069. Toxicity toward hypoxic tumor cells in vivo is demonstrated by clamping tumors (for 60 min) following administration of PD 130908. Systemic toxicity is substantially reduced following oral drug administration. Further, doses achievable following fractionated drug treatments are sufficiently high to produce significant levels of radiosensitization.
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- 供应商TargetMol规格货期6-8周纯度-¥ 10,600.001
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