Name: PF-06465603
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212713318
Cas No:1431626-44-6
常用名:PF-06465603
别名:PF06465603, PF 06465603
IUPAC:2-{[(1r,4r)-4-[2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxy}acetic acid
IUPAC:2-{[(1r,4r)-4-[2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-8-yl]cyclohexyl]oxy}acetic acid
InChI key:FYGAMXOBXPHZMN-SHTZXODSSA-N

分子式:C22H25N5O5
分子量:439.472
氢键供体数 (HBD):2
氢键受体数 (HBA):9
LogP:0.7126563
SMILES:COc1ccc(cn1)-c1cc2c(C)nc(N)nc2n([C@H]2CC[C@@H](CC2)OCC(O)=O)c1=O |wU:22.27,wD:19.20,(-4,-6.93,;-4,-5.39,;-2.67,-4.62,;-1.33,-5.39,;,-4.62,;,-3.08,;-1.33,-2.31,;-2.67,-3.08,;1.33,-2.31,;2.67,-3.08,;4,-2.31,;5.33,-3.08,;5.33,-4.62,;6.67,-2.31,;6.67,-.77,;8,,;5.33,,;4,-.77,;2.67,,;2.67,1.54,;4,2.31,;4,3.85,;2.67,4.62,;1.33,3.85,;1.33,2.31,;2.67,6.16,;1.33,6.93,;1.33,8.47,;2.67,9.24,;,9.24,;1.33,-.77,;)|
SMILES:COc1ccc(cn1)-c1cc2c(C)nc(N)nc2n([C@H]2CC[C@@H](CC2)OCC(O)=O)c1=O |wU:22.27,wD:19.20,(-4,-6.93,;-4,-5.39,;-2.67,-4.62,;-1.33,-5.39,;,-4.62,;,-3.08,;-1.33,-2.31,;-2.67,-3.08,;1.33,-2.31,;2.67,-3.08,;4,-2.31,;5.33,-3.08,;5.33,-4.62,;6.67,-2.31,;6.67,-.77,;8,,;5.33,,;4,-.77,;2.67,,;2.67,1.54,;4,2.31,;4,3.85,;2.67,4.62,;1.33,3.85,;1.33,2.31,;2.67,6.16,;1.33,6.93,;1.33,8.47,;2.67,9.24,;,9.24,;1.33,-.77,;)|

PF-06465603 is a metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~