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HIT212713422
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HIT212713422
  • HIT ID:HIT212713422
  • Cas No:157824-23-2
  • 常用名:R-84760 hydrochloride
  • 别名:R-86436 hydrochloride, R86436 hydrochloride, R84760 hydrochloride, R 86436 hydrochloride, R 84760 hydrochloride
    别名:R-86436 hydrochloride, R86436 hydrochloride, R84760 hydrochloride, R 86436 hydrochloride, R 84760 hydrochloride
  • IUPAC:(3R)-4-[(1S)-5,6-dichloro-2,3-dihydro-1H-indene-1-carbonyl]-3-[(pyrrolidin-1-yl)methyl]thiomorpholine hydrochloride
    IUPAC:(3R)-4-[(1S)-5,6-dichloro-2,3-dihydro-1H-indene-1-carbonyl]-3-[(pyrrolidin-1-yl)methyl]thiomorpholine hydrochloride
  • InChI key:KSUNRZWFIKXTKO-LIOBNPLQSA-N
  • 分子式:C19H25Cl3N2OS
  • 分子量:435.83
  • 氢键供体数 (HBD):0
  • 氢键受体数 (HBA):2
  • LogP:3.8975425
  • SMILES:Cl.Clc1cc2CC[C@H](C(=O)N3CCSC[C@H]3CN3CCCC3)c2cc1Cl
    SMILES:Cl.Clc1cc2CC[C@H](C(=O)N3CCSC[C@H]3CN3CCCC3)c2cc1Cl
  • R-84760 is a κ-opioid receptor agonist. R-84760 produces an extremely potent antinociceptive effect against tonic pain through the kappa-opioid receptors; the sites of action of subcutaneously administered R-84760 are the supraspinal and spinal loci in the central nervous system; and a part of the mechanism of the antinociceptive effect of R-84760 is activation of the descending noradrenergic pathway.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    8-10周
    纯度
    -
    ¥ 12,800.00
    1

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