Name: SRTCX1003
Rating: 5 (10 reviews)

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HIT ID:HIT212713731
Cas No:1203480-86-7
常用名:SRTCX1003
别名:SRTCX-1003, SRTCX 1003
IUPAC:2-{2-[2-(morpholin-4-yl)ethoxy]phenyl}-N-(1,3-thiazol-2-yl)-1H-1,3-benzodiazole-4-carboxamide
IUPAC:2-{2-[2-(morpholin-4-yl)ethoxy]phenyl}-N-(1,3-thiazol-2-yl)-1H-1,3-benzodiazole-4-carboxamide
InChI key:BXSJTHFUADFIKS-UHFFFAOYSA-N

分子式:C23H23N5O3S
分子量:449.53
氢键供体数 (HBD):2
氢键受体数 (HBA):6
LogP:3.3616745
SMILES:O=C(Nc1nccs1)c1cccc2[nH]c(nc12)-c1ccccc1OCCN1CCOCC1
SMILES:O=C(Nc1nccs1)c1cccc2[nH]c(nc12)-c1ccccc1OCCN1CCOCC1

SRTCX1003, a SIRT1 activator, suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.

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