Name: UR-1505
Rating: 5 (10 reviews)

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HIT ID:HIT212713848
Cas No:651331-92-9
常用名:UR-1505
别名:UR1505, UR 1505
IUPAC:2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid
IUPAC:2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid
InChI key:BLEWPNAUDGZWPU-UHFFFAOYSA-N

分子式:C10H7F5O4
分子量:286.154
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:3.475331
SMILES:OC(=O)c1ccc(OCC(F)(F)C(F)(F)F)cc1O
SMILES:OC(=O)c1ccc(OCC(F)(F)C(F)(F)F)cc1O

UR-1505 is a nuclear factor of activated T cells (NF-AT) inhibitor. UR-1505 acts by inhibiting T cell activation depending on T cell receptor signaling pathway. Furthermore, the antiproliferative effects of UR-1505 are not a consequence of decreased cell viability.

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