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- HIT ID:HIT212713945
- Cas No:332922-63-1
- 常用名:STOCK2S-26016
- 别名:WNK-IN-B, WNK IN B, Compound B
- InChI key:PGNWQNJXXLPZEL-UHFFFAOYSA-N
- 分子式:C20H19N3O2
- 分子量:333.391
- 氢键供体数 (HBD):2
- 氢键受体数 (HBA):4
- LogP:3.1339362
- WNK-IN-B is an inhibitor of Wnk signalling. WNK-IN-B is a cell-permeable diaminoacridine derivative that targets the CCT domain of SPAK and OSR1 via reversible binding. WNK-IN-B selectively suppress hypotonic shock-induced WNK signaling pathway activation in mpkDCT and MOVAS (100 µM) cultures without affecting p38 MAPK phosphorylation.
市场产品/服务共显示2个结果
- 供应商TargetMol规格货期5日内发货纯度-¥ 3,130.001
- 供应商TimTec规格货期4-6周纯度-¥ 1,320.001
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